non-linear logistic model with least squares algorism graphpad prism 6 Search Results


90
Becton Dickinson facscalibur flow cytometer
Facscalibur Flow Cytometer, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NanoTemper Technologies analysis software
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LI-COR odyssey imaging system
Odyssey Imaging System, supplied by LI-COR, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Promega glomax multi+ plate reader
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Tibotec Pharmaceuticals rilpivirine
<t>Rilpivirine</t> Cross-Resistance of HIV-1 from 100 Individuals Failing First-Line Antiretroviral Therapy. The adjusted IC 90 was calculated by multiplying the IC 50 by 2 to approximate IC 90 values and applying a rilpivirine (RPV) human serum binding factor (18.5) as determined in rilpivirine susceptibility experiments comparing human serum and fetal bovine serum (data not shown). RPV FC values were determined by dividing the IC 90 generated for each plasma-derived virus by a composite IC 90 from 12 treatment-naive plasma-derived viruses collected form the same geographical region. The dashed line indicates the RPV phenotypic biological cutoff of 2.5 FC. The IC 90 values of samples 90 through 100 exceeded the highest concentration of RPV that could be tested in TZMbl cells without cytotoxicity and are reported as >340 ng/mL.
Rilpivirine, supplied by Tibotec Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ApexBio ro3306
<t>Rilpivirine</t> Cross-Resistance of HIV-1 from 100 Individuals Failing First-Line Antiretroviral Therapy. The adjusted IC 90 was calculated by multiplying the IC 50 by 2 to approximate IC 90 values and applying a rilpivirine (RPV) human serum binding factor (18.5) as determined in rilpivirine susceptibility experiments comparing human serum and fetal bovine serum (data not shown). RPV FC values were determined by dividing the IC 90 generated for each plasma-derived virus by a composite IC 90 from 12 treatment-naive plasma-derived viruses collected form the same geographical region. The dashed line indicates the RPV phenotypic biological cutoff of 2.5 FC. The IC 90 values of samples 90 through 100 exceeded the highest concentration of RPV that could be tested in TZMbl cells without cytotoxicity and are reported as >340 ng/mL.
Ro3306, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ApexBio nsc663284
<t>Rilpivirine</t> Cross-Resistance of HIV-1 from 100 Individuals Failing First-Line Antiretroviral Therapy. The adjusted IC 90 was calculated by multiplying the IC 50 by 2 to approximate IC 90 values and applying a rilpivirine (RPV) human serum binding factor (18.5) as determined in rilpivirine susceptibility experiments comparing human serum and fetal bovine serum (data not shown). RPV FC values were determined by dividing the IC 90 generated for each plasma-derived virus by a composite IC 90 from 12 treatment-naive plasma-derived viruses collected form the same geographical region. The dashed line indicates the RPV phenotypic biological cutoff of 2.5 FC. The IC 90 values of samples 90 through 100 exceeded the highest concentration of RPV that could be tested in TZMbl cells without cytotoxicity and are reported as >340 ng/mL.
Nsc663284, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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TotalLab Ltd phoretix 1d
<t>Rilpivirine</t> Cross-Resistance of HIV-1 from 100 Individuals Failing First-Line Antiretroviral Therapy. The adjusted IC 90 was calculated by multiplying the IC 50 by 2 to approximate IC 90 values and applying a rilpivirine (RPV) human serum binding factor (18.5) as determined in rilpivirine susceptibility experiments comparing human serum and fetal bovine serum (data not shown). RPV FC values were determined by dividing the IC 90 generated for each plasma-derived virus by a composite IC 90 from 12 treatment-naive plasma-derived viruses collected form the same geographical region. The dashed line indicates the RPV phenotypic biological cutoff of 2.5 FC. The IC 90 values of samples 90 through 100 exceeded the highest concentration of RPV that could be tested in TZMbl cells without cytotoxicity and are reported as >340 ng/mL.
Phoretix 1d, supplied by TotalLab Ltd, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 97 stars, based on 1 article reviews
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ATCC staphylococcus sp
<t>Rilpivirine</t> Cross-Resistance of HIV-1 from 100 Individuals Failing First-Line Antiretroviral Therapy. The adjusted IC 90 was calculated by multiplying the IC 50 by 2 to approximate IC 90 values and applying a rilpivirine (RPV) human serum binding factor (18.5) as determined in rilpivirine susceptibility experiments comparing human serum and fetal bovine serum (data not shown). RPV FC values were determined by dividing the IC 90 generated for each plasma-derived virus by a composite IC 90 from 12 treatment-naive plasma-derived viruses collected form the same geographical region. The dashed line indicates the RPV phenotypic biological cutoff of 2.5 FC. The IC 90 values of samples 90 through 100 exceeded the highest concentration of RPV that could be tested in TZMbl cells without cytotoxicity and are reported as >340 ng/mL.
Staphylococcus Sp, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ATCC mycobacterium smegmatis lehmann and neumann
<t>Rilpivirine</t> Cross-Resistance of HIV-1 from 100 Individuals Failing First-Line Antiretroviral Therapy. The adjusted IC 90 was calculated by multiplying the IC 50 by 2 to approximate IC 90 values and applying a rilpivirine (RPV) human serum binding factor (18.5) as determined in rilpivirine susceptibility experiments comparing human serum and fetal bovine serum (data not shown). RPV FC values were determined by dividing the IC 90 generated for each plasma-derived virus by a composite IC 90 from 12 treatment-naive plasma-derived viruses collected form the same geographical region. The dashed line indicates the RPV phenotypic biological cutoff of 2.5 FC. The IC 90 values of samples 90 through 100 exceeded the highest concentration of RPV that could be tested in TZMbl cells without cytotoxicity and are reported as >340 ng/mL.
Mycobacterium Smegmatis Lehmann And Neumann, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Rilpivirine Cross-Resistance of HIV-1 from 100 Individuals Failing First-Line Antiretroviral Therapy. The adjusted IC 90 was calculated by multiplying the IC 50 by 2 to approximate IC 90 values and applying a rilpivirine (RPV) human serum binding factor (18.5) as determined in rilpivirine susceptibility experiments comparing human serum and fetal bovine serum (data not shown). RPV FC values were determined by dividing the IC 90 generated for each plasma-derived virus by a composite IC 90 from 12 treatment-naive plasma-derived viruses collected form the same geographical region. The dashed line indicates the RPV phenotypic biological cutoff of 2.5 FC. The IC 90 values of samples 90 through 100 exceeded the highest concentration of RPV that could be tested in TZMbl cells without cytotoxicity and are reported as >340 ng/mL.

Journal: Antiviral Chemistry & Chemotherapy

Article Title: Frequent cross-resistance to rilpivirine among subtype C HIV-1 from first-line antiretroviral therapy failures in South Africa

doi: 10.1177/2040206618762985

Figure Lengend Snippet: Rilpivirine Cross-Resistance of HIV-1 from 100 Individuals Failing First-Line Antiretroviral Therapy. The adjusted IC 90 was calculated by multiplying the IC 50 by 2 to approximate IC 90 values and applying a rilpivirine (RPV) human serum binding factor (18.5) as determined in rilpivirine susceptibility experiments comparing human serum and fetal bovine serum (data not shown). RPV FC values were determined by dividing the IC 90 generated for each plasma-derived virus by a composite IC 90 from 12 treatment-naive plasma-derived viruses collected form the same geographical region. The dashed line indicates the RPV phenotypic biological cutoff of 2.5 FC. The IC 90 values of samples 90 through 100 exceeded the highest concentration of RPV that could be tested in TZMbl cells without cytotoxicity and are reported as >340 ng/mL.

Article Snippet: RPV was obtained through the AIDS Research and Reference Reagent Program, Division of AIDS, NIAID, NIH: Rilpivirine (Cat# 12147) from Tibotec Pharmaceuticals, Inc. Four-parameter, non-linear regression for curve fitting was used to generate IC 50 values using GraphPad Prism 6 software (GraphPad Software, Inc).

Techniques: Binding Assay, Generated, Clinical Proteomics, Derivative Assay, Virus, Concentration Assay

Cross-Resistance to  Rilpivirine  of Plasma-Derived Viruses from Individuals on Failing First-Line NNRTI-Based ART.

Journal: Antiviral Chemistry & Chemotherapy

Article Title: Frequent cross-resistance to rilpivirine among subtype C HIV-1 from first-line antiretroviral therapy failures in South Africa

doi: 10.1177/2040206618762985

Figure Lengend Snippet: Cross-Resistance to Rilpivirine of Plasma-Derived Viruses from Individuals on Failing First-Line NNRTI-Based ART.

Article Snippet: RPV was obtained through the AIDS Research and Reference Reagent Program, Division of AIDS, NIAID, NIH: Rilpivirine (Cat# 12147) from Tibotec Pharmaceuticals, Inc. Four-parameter, non-linear regression for curve fitting was used to generate IC 50 values using GraphPad Prism 6 software (GraphPad Software, Inc).

Techniques: Clinical Proteomics

Association of NNRTI resistance mutations with  rilpivirine  cross-resistance.

Journal: Antiviral Chemistry & Chemotherapy

Article Title: Frequent cross-resistance to rilpivirine among subtype C HIV-1 from first-line antiretroviral therapy failures in South Africa

doi: 10.1177/2040206618762985

Figure Lengend Snippet: Association of NNRTI resistance mutations with rilpivirine cross-resistance.

Article Snippet: RPV was obtained through the AIDS Research and Reference Reagent Program, Division of AIDS, NIAID, NIH: Rilpivirine (Cat# 12147) from Tibotec Pharmaceuticals, Inc. Four-parameter, non-linear regression for curve fitting was used to generate IC 50 values using GraphPad Prism 6 software (GraphPad Software, Inc).

Techniques:

Combined effect of NNRTI resistance mutations on RPV cross-resistance. FC resistance was evaluated based on the contribution of the number of RPV-associated mutations (L100I, K101E/P, E138A/G/K/Q/R, V179L, Y181C/I/V, Y188L, H221Y, F227C and M230I/L) per sample with and without K103N. Samples are grouped based on having zero, one or two RPV-associated mutations. Samples containing three or more RPV-associated mutations could not be evaluated due to insufficient numbers. Samples with zero RPV-associated mutations include the 12 treatment-naïve individuals that were used as wild-type comparators in this study. Each group displays box-and-whisker plots of interquartile FC ranges for all samples in the category (white), samples without K103N (shaded) and samples containing K103N (diagonal stripes). The dotted red line indicates the RPV phenotypic resistance biological cutoff of 2.5 FC. RPV: rilpivirine.

Journal: Antiviral Chemistry & Chemotherapy

Article Title: Frequent cross-resistance to rilpivirine among subtype C HIV-1 from first-line antiretroviral therapy failures in South Africa

doi: 10.1177/2040206618762985

Figure Lengend Snippet: Combined effect of NNRTI resistance mutations on RPV cross-resistance. FC resistance was evaluated based on the contribution of the number of RPV-associated mutations (L100I, K101E/P, E138A/G/K/Q/R, V179L, Y181C/I/V, Y188L, H221Y, F227C and M230I/L) per sample with and without K103N. Samples are grouped based on having zero, one or two RPV-associated mutations. Samples containing three or more RPV-associated mutations could not be evaluated due to insufficient numbers. Samples with zero RPV-associated mutations include the 12 treatment-naïve individuals that were used as wild-type comparators in this study. Each group displays box-and-whisker plots of interquartile FC ranges for all samples in the category (white), samples without K103N (shaded) and samples containing K103N (diagonal stripes). The dotted red line indicates the RPV phenotypic resistance biological cutoff of 2.5 FC. RPV: rilpivirine.

Article Snippet: RPV was obtained through the AIDS Research and Reference Reagent Program, Division of AIDS, NIAID, NIH: Rilpivirine (Cat# 12147) from Tibotec Pharmaceuticals, Inc. Four-parameter, non-linear regression for curve fitting was used to generate IC 50 values using GraphPad Prism 6 software (GraphPad Software, Inc).

Techniques: Whisker Assay